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Biology

CAIE2022

3 ( iii) Explain why the enzym e Taq polymerase, rather than any other type of DNA polymerase, is used in PCR. ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [2] ( b) The presence of a faulty allele of the gene BRCA2 can lead to an increased chance of developing breast cancer. There are many different faulty alleles of the gene BRCA2. People who are considered to be at risk of breast cancer may choose to be tested for the presence of these alleles in their genomes. A microarray can be used to test blood samples for the presence of these alleles. The microarray contains DNA probes for different faulty alleles of the BRCA2 gene. ( i) State the meaning of the term genome. ........................................................................................................................................... ........................................................................................................................................... ...................................................................................................................................... [1] ( ii) Suggest which type of cell from a blood sample is suitable for testing for the presence of these faulty alleles. G ive a reason for your choice. type of cell ......................................................................................................................... reason ............................................................................................................................... ........................................................................................................................................... [1] © UCLES 2019 97 00/04/SP/22 [Turn over PMT

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Biology

CAIE2016

(a) Explain how the lac operon is involved in the metabolism of lactose in Escherichia coli. [9] (b) Describe the role of gibberellin in the germination of barley. [6] [Total: 15] ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... ................................................................................................................................................... © UCLES 2014 9700/04/SP/16 PPMMTT

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